Dr. Mannarino was raised in Mingo Junction, Ohio and attended Steubenville Catholic Central High School. He then matriculated to Columbus, Ohio, earning a Bachelors Degree in Biology with a minor in Sociology at THE Ohio State University. Continuing his education further, he received his Doctorate in Optometry from Indiana University in Bloomington, Indiana.

Dr. Mannarino lives in Lewis Center, Ohio, where he enjoys staying active by playing basketball, tennis, football, hiking, and cheering on all things Buckeyes.